The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens.

There are many academic references describing how RMs are made, but few that explain why they are used, how they should be used and what happens when they are not properly used. In order to fill this gap, the editors have taken the contributions of more than thirty RM practitioners to produce a highly readable text organized in nine chapters. Starting with an introduction to historical, theoretical and technical requirements, the book goes on to examine all aspects of RM production from planning, preparation through analysis to certification, reviews recent development areas, RMs for life analysis and some important general application fields, considers the proper usage of RMs, gives advice on availability and sources of information and lastly looks at future trends and needs for RMs. This book is intended to be a single point of information that both guides the reader through the use of RMs and serves as a primary reference source. It should be on the reading list of anyone working in an analytical laboratory and be found on the library shelf of all analytical chemical laboratories.

Statistical methodology plays a key role in ensuring that DNA evidence is collected, interpreted, analyzed and presented correctly. With the recent advances in computer technology, this methodology is more complex than ever before. There are a growing number of books in the area but none are devoted to the computational analysis of evidence. This book presents the methodology of statistical DNA forensics with an emphasis on the use of computational techniques to analyze and interpret forensic evidence.

Bipolar depression is now known to exist as a spectrum of disorders rather than a single disease entity. Bipolar II Disorder exists on this spectrum as a condition where the depressive episodes are as severe as in Bipolar I Disorder, but where the mood elevation states are not as extreme. This unexpected combination can lead to a failure to detect a condition thought to affect up to 6% of the population. This book reviews, for the first time, our knowledge of this debilitating disorder, covering its history, classification and neurobiology. In a unique section, fourteen internationally recognized experts debate management strategies, building to some consensus, and resulting in treatment guidelines where no such advice currently exists. It should be read by all health professionals managing mood disorders and will be informative to those wishing to learn more about the condition.

Given that chemicals in over 1,400 (mainly household) products can be intentionally inhaled for their psychoactive and mind-altering effects, it's not surprising that inhalants are the most commonly abused drug in the United States today, especially among young people. In spite of their popularity, however, very little is known about how these chemicals act on the brain and body. This book provides valuable information on the history of inhalant abuse, the major classes of the most commonly abused inhalants, what scientists currently know about the effects of inhalants on the brain and body, trends in inhalant abuse, and treatment and prevention measures.

This book constitutes a timely contribution to the existing literature by presenting a relatively comprehensive, neurobiological account of certain aspects of second language acquisition. It represents the collaborative efforts of members of the Neurobiology of Language Research Group in the Applied Linguistics and TESL Department at UCLA. Members of the group are trained in neurobiology and then use this knowledge to develop biological accounts of various aspects of applied linguistics.